In this article, we show that conolidine, a all-natural analgesic alkaloid used in standard Chinese medication, targets ACKR3, thereby providing supplemental evidence of a correlation between ACKR3 and suffering modulation and opening choice therapeutic avenues to the treatment of Long-term agony. Tabernaemontana divaricata Conolidine is an indole alkaloid. Preliminary https://bertolto478nhf5.wikirecognition.com/user