If the pathogenic variant found in the proband can't be detected while in the leukocyte DNA of possibly parent, the recurrence chance to sibs is approximated to get one% according to the theoretic likelihood of parental germline mosaicism. Platelet rely and serum LDH concentration are probably the most delicate markers https://martinmrtxz.weblogco.com/32292881/the-2-minute-rule-for-air-handling-unit-ahu-hire