Sedative medicines which include benzodiazepines or connected medication: The concomitant usage of opioids with sedative medicines such as benzodiazepines or similar medications improves the chance of sedation, respiratory despair, coma and Demise due to additive CNS depressant impact. The dose and duration of concomitant use really should be constrained (see https://luisl158elt2.popup-blog.com/profile